The first all-female GP team to win a British Business Bank ECF mandate just closed £45M, and its medtech portfolio is already in the US — TFN

• THENA Capital has closed its inaugural £45 million Fund I: the primary all-female GP-led fund to obtain backing from the British Enterprise Financial institution’s Enterprise Capital Funds programme.

• In its first yr, the fund has backed 5 UK medtech firms, one in every of which has already launched within the US in collaboration with the Mayo Clinic, and one other that has obtained MHRA CE marking for IVD standing.

• The LP base consists of Baroness Martha Lane Fox, chair of BlackRock Switzerland, and senior executives from GSK, Novartis, AstraZeneca, Carlyle, and Hellman & Friedman: over 50% of whom are girls.

The structural argument for specialist medtech capital within the UK has been made many occasions. THENA Capital is doing issues in another way, with 5 portfolio firms in its first yr, a Mayo Clinic collaboration, an MHRA regulatory approval, and an NHS Innovation Accelerator choice earlier than the fund has even completed deploying.

London-based VC agency has closed Fund I at £45 million, following a primary shut of £27 million in March 2025. The fund is anchored by the British Enterprise Financial institution’s Enterprise Capital Funds programme, making THENA the primary all-female Normal Accomplice-led fund to obtain ECF backing.

Fund I targets roughly 25 firms, investing £500k to £1 million in seed-stage digital well being platforms and fast-track medical gadgets with a confirmed pathway from UK origination to US-scale commercialisation. Fund I is now totally closed.

“THENA Capital’s profitable last shut and powerful tempo of early deployment reveal the worth of specialist buyers with deep sector experience and clear business focus. By means of the Enterprise Capital Funds programme, we purpose to assist groups like THENA which might be addressing structural gaps within the UK’s fairness ecosystem,” says Mark Sims, managing director and head of improvement fairness funds, British Enterprise Financial institution.

“As a founding signatory of the Investing in Ladies Code, we’re happy to proceed our partnership with an all-female funding crew who’ve additionally signed the Code,” he provides.

Three founders, one thesis

THENA was based in 2021 by three healthcare business execs: Dr Pamela Walker Geddes, who has labored with Pfizer, Roche, Novartis, Abbott, Sanofi, Bayer, Boston Scientific, Medtronic, and GE Healthcare, and is a member of Jesus School’s Funding Committee on the College of Oxford; Esther Reynal de Saint-Michel, a McKinsey-trained business strategist with partnerships together with GlaxoSmithKline, Reckitt, Unilever, and Johnson & Johnson; and Tatum Yount Getty, a client well being and wellness chief who scaled SoulCycle, Tonal, and Barry’s, with business partnerships together with Nike, Spotify, and Fitbit. Tatum additionally sits on the Board of Trustees of the Tate Basis.

The thesis is particular: UK medtech produces world-class science however lacks the commercially minded, transatlantically related capital wanted to succeed in sufferers at scale. THENA’s technique is to originate investments at UK seed valuations and construct portfolio firms towards US institutional entry at Sequence A and past.

“Origination at THENA begins with a really particular query: the place is outstanding UK medtech innovation being undercapitalised relative to its scientific and business potential? Our investments span completely different elements of the healthcare system, however they share the identical fundamentals — robust scientific want, validated expertise, a reputable path to scale, and the potential to develop into category-defining firms pushed by dedicated and outcomes-oriented founders,” notes Reynal de Saint-Michel.

5 firms in 12 months

THENA has already deployed into 5 portfolio firms throughout three verticals: affected person assist, care supply, and medical merchandise.

• Plexāā launched within the US market with its first product, BLOOM⁴³, and commenced a improvement collaboration with Mayo Clinic, which joined the cap desk.
• Salient Bio obtained UK CE-marked IVD standing from the MHRA for its IBD diagnostic check, formal regulatory validation earlier than most seed-stage firms have a product available on the market.
• Sanome closed its seed spherical with co-investment from THENA’s personal LP base.
• Heim Well being was chosen for the 2026 NHS Innovation Accelerator cohort, one of the vital aggressive early commercialisation programmes in UK well being innovation.
• Zonova accomplished its funding with THENA as lead, rounding out a portfolio that spans the complete scientific pathway from prognosis to therapy to affected person monitoring.

“Having THENA Capital on our cap desk has been invaluable. The variety of backgrounds and experience throughout their crew means we profit from a wealth of views — from opening doorways to well being programs and the broader US ecosystem, to serving to us assume creatively and bringing insights which have formed how we strategy scaling from the UK into the US market,” says Saahil Mehta, founder and CEO, Plexāā.

“At first of this fundraiser, Zonova’s best want was to draw backing from buyers who actually ‘received’ what the corporate and its mission are about. THENA Capital is a dream ticket, amplified by a gaggle of fantastic buyers who carry a lot to the corporate. We’re excited to be constructing with them,” provides Verity Baldry, chair, Zonova.

The £45 million fund was assembled with uncommon intentionality.

Over 50% of LPs are feminine. The investor base consists of Baroness Martha Lane Fox, co-founder of Lastminute.com; Mirjam Staub-Bisang, chair and senior advisor at BlackRock Switzerland; and Patrick Healy, CEO of Hellman & Friedman.

Senior pharma executives from GSK, Novartis, and AstraZeneca sit alongside senior professionals from Carlyle, TA Associates, Vista Fairness, and GHO Capital, Europe’s main specialist healthcare fund. Household places of work Firebird Collective and This Day Basis are additionally dedicated to the fund.

The excellence issues operationally. Pharma and personal fairness LPs at THENA present direct exit intelligence, casual entry to M&A pathways, and the sector credibility that portfolio firms inherit from their first board assembly onward.

“The UK medtech ecosystem has by no means lacked expertise or ambition. What it has traditionally lacked is the sort of commercially-minded, transatlantically-connected capital that THENA gives. Fund I closing at £45 million, in a tough fundraising surroundings, and deploying into 5 firms in its first yr is an announcement about each the standard of this crew and the dimensions of the chance they’re addressing,” provides Ponti.

The community behind the fund

Earlier than elevating a single pound, the THENA founding crew spent 4 years constructing the Way forward for HealthTech Hub, a group of over 400 members spanning founders, clinicians, payers, suppliers, pharma executives, and healthcare buyers, alongside a Fellows Community of over 50 business specialists within the UK and US.

Over 20 transatlantic occasions have been hosted thus far. The origination benefit this creates compounds with each fund cycle: as portfolio firm founders graduate into the group as mentors, co-founders, and deal sources, the community deepens.

“What we have now inbuilt THENA shouldn’t be a fund, it’s a platform. The FoHH group, our transatlantic business community by way of our Fellows, and the 150+ merchandise our crew has collectively delivered to market are structural benefits that took years to construct. Fund I is the proof level. The 5 firms we have now backed on this first yr reveal precisely what is feasible when the appropriate capital meets the appropriate assist infrastructure,” says Walker Geddes.

“The individuals who engaged with us early did so as a result of they understood what we had been constructing, not as a result of we advised them to. That’s the relationship we intend to have with each accomplice on this agency’s future. Fund I is the inspiration. Fund II is the place the franchise turns into seen,” provides Yount Getty.

Market context

In response to Statista, the UK digital well being market is projected to succeed in $7.45 billion by 2030, rising at a CAGR of 6.97% from 2025.

As TFN reported in its IWD 2026 analysis, female-only based groups make up simply 6% of the enterprise capital market, and the quantity they elevate has stagnated since 2016, making a £45 million ECF-backed shut by an all-female GP crew a structural milestone, not only a fundraising milestone.

The 01Health Series A we coated this week, one other female-founded UK healthtech firm backed by Balderton, underscores how the class is attracting critical institutional capital for the primary time.

Fund II is the place, as Yount Getty places it, “the franchise turns into seen.” Whether or not THENA’s first five-year portfolio firms, one already in US deployment with Mayo Clinic, can generate the exits that validate the mannequin is the check the subsequent two to 3 years will reply.